Faculty of a 1000 rated our Nature Methods papers "must read"!
Micheal Pirrung evaluated our paper on 23 Jan 2006: "This article provides the first new chromophore useful for the caging of bioactive molecules in quite some time. The NDBF group has a very high absorptivity and an excellent quantum yield, which make its photochemical deprotection one of the most efficient known. The NDBF group also has a reasonable two-photon cross section that enables it to be used in two-photon uncaging, giving high spatial control and minimal damage to living systems."
http://www.f1000biology.com/article/16369551/evaluation
Pirrung is chemist who is a pioneer in the development of caged compounds. His most imporant work is probably the development of the original photoaddressable organic-synthesis-on-a-chip technique with Fodor and Stryer that formed the basis of the technology used by Affymetrix (Science (1991) 251:767).
Micheal Pirrung evaluated our paper on 23 Jan 2006: "This article provides the first new chromophore useful for the caging of bioactive molecules in quite some time. The NDBF group has a very high absorptivity and an excellent quantum yield, which make its photochemical deprotection one of the most efficient known. The NDBF group also has a reasonable two-photon cross section that enables it to be used in two-photon uncaging, giving high spatial control and minimal damage to living systems."
http://www.f1000biology.com/article/16369551/evaluation
Pirrung is chemist who is a pioneer in the development of caged compounds. His most imporant work is probably the development of the original photoaddressable organic-synthesis-on-a-chip technique with Fodor and Stryer that formed the basis of the technology used by Affymetrix (Science (1991) 251:767).
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